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Dimensional memory in glioblastoma mechanics: Traction force analysis of cells cultured in 2D versus 3D collagen environments.

Bioact Mater · 2026 · PMC12514354 · PMID 41078868

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borderline significanceno p-value reported
For example, HMC3 FA number (p = 0.051) has d = 0.83, indicating a large difference despite borderline significance [ 146 ]. 3 Conclusions In summary, our study demonstrates that the dimensionality of the pre-culture environment imparts a mechanical memory to glioblastoma cells that persists even when they are reseeded onto standardized 2D surfaces.

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