MMPs and NETs are detrimental in CNS-tuberculosis with MMP Inhibition in CNS-tuberculosis mice improving survival.

Notably, a smaller number of AFB positive granulomas is observed in the group that received ATT + SB-3CT relative to VC ( P = 0.0036) or ATT alone ( P = 0.0155), and a decreasing trend is observed in the ATT + Doxycycline group (Fig. 5 G).

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