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Evaluating biased agonism of glucagon-like peptide-1 (GLP-1) receptors to improve cellular bioenergetics: A systematic review.

Diabetes Obes Metab · 2025 · PMC12515783 · PMID 40726453

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an observed trendno p-value reported
24 Moreover, when comparing controls and knockout mice, both groups had equivalent areas under the curves and had an observed trend of significantly decreased glucose levels at 6 h post‐treatment. 24 When replicated with semaglutide and tirzepatide, beta‐arrestin knockout mice exhibited improved glucose responses at 24 and 72 h post‐treatment.

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