Serum Transthyretin as Prognostic Biomarker for Cardiovascular Events and Mortality: A Systematic Review and Meta-Analysis.

JACC Adv · 2025 · PMC12517089 · PMID 41037847

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0.0900

closest p · 1.8× alpha

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boldest claim

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a nonsignificant trendP = 0.09so close (0.05 < p ≤ 0.1)

The predictive value of serum TTR levels was also enhanced in populations with higher percentage of HF patients ( P = 0.009) ( Supplemental Figure 4 ), in cohorts with elevated serum creatinine levels ( P < 0.001) and showed a nonsignificant trend in studies with higher percentage of coronary artery disease patients ( P = 0.09) ( Supplemental Figure 5 ).

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