As an overall trend as (SD, Normal) (HFD, Normal) (HFD, NAFL) (HFHC, NAFL) (HFHC, NASH), the most populous cluster C shifts from Cluster 3 to 4 in chemo-spatial clustering and the most populous cluster shifts from Cluster to in chemical clustering (see and attached to each figure vertically and horizontally in Fig. 4 b).
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Integrating spatial and chemical information enhances differentiation of non-alcoholic steatohepatitis states in Raman imaging.
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