The partial likelihood deviance plot showed a decreasing trend with increasing log(λ), reaching a minimum at approximately log(λ) = − 3, which suggests an optimal λ value of approximately 0.001, indicating that the genes selected at this point are most relevant for predicting the prognosis of OS patients treated with Shikonin (Supplementary Fig. 2B).
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PH responsive hydrogel nanocomposites for targeted Shikonin delivery enhance anti PDL1 immunotherapy in osteosarcoma.
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