Exploring the relationship between GBA1 host genotype and gut microbiome in the GBA1 L444P/WT mouse model: implications for Parkinson's disease pathogenesis.

Front Neurosci · 2025 · PMC12521094 · PMID 41103722

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

a trend towards significancep = 0.053so close (0.05 < p ≤ 0.1)

At 6 months, the median weight of the L444P/WT group was significantly higher than the one in the WT/WT group ( p = 0.017), but the difference between 3 and 6 months (delta weight) only showed a trend towards significance, being higher in L444P/WT ( p = 0.053).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Exploring the relationship between &lt;i&gt;GBA1&lt;/i&gt; host genotype and gut microbiome in the &lt;i&gt;GBA1&lt;/i&gt; &lt;sup&gt;L444P/WT&lt;/sup&gt; mouse model: implications for Parkinson's disease pathogenesis.

The sentences

Exploring the relationship between <i>GBA1</i> host genotype and gut microbiome in the <i>GBA1</i> <sup>L444P/WT</sup> mouse model: implications for Parkinson's disease pathogenesis.