borderline significancep = 0.05
Four of the studies showed the pooled estimates of mean difference in the change of HAMA scores between acupuncture plus paroxetine or duloxetine group and medication alone group were statistically significant at week 4 (−1.94, 95%CI: −3.71 to −0.17; p = 0.03) with borderline significance at week 6/8 (−3.17, 95%CI: −6.38 to 0.04; p = 0.05) from baseline.