Pregnane X receptor (PXR) as a prognostic marker and therapeutic target in kidney renal clear cell carcinoma (KIRC) via AMPK pathway regulation.

Sci Rep · 2025 · PMC12521680 · PMID 41087473

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a decreasing trendno p-value reported

In the PXR-knockdown group (siRNA group), the expression level of p-AMPK was approximately twice that of the NC group, while the p-PI3K/PI3K and p-AKT/AKT ratios showed a decreasing trend compared to the NC group.

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