Approximately one-third of RA cases have their onset in older adults, with a rising incidence between the fifth and sixth decades of life, a peak prevalence around the age of 80 [ 39 ], and an increasing trend [ 40 ].
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Rheumatoid Arthritis and Osteoporosis as Prototypes of Immunosenescence in Osteoimmunology: Molecular Pathways of Inflammaging and Targeted Therapies.
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