Barely Significant
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Long noncoding RNA TMPO-AS1 upregulates chromosomal passenger complex expression to promote cell proliferation in lung cancer via sponging microRNA let-7b-5p.

Cell Div · 2025 · PMC12529790 · PMID 41094477

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highly significantno p-value reported
Notably, we observed this effect to be highly significant in smoker cohorts, suggesting that environmental carcinogens such as nicotine and NNK may enhance CPC activity through direct molecular interactions, as supported by our docking studies.

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