Barely Significant
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Efficacy and safety of edaravone dexborneol in acute ischemic stroke: systematic review and meta-analysis.

Front Neurol · 2025 · PMC12532774 · PMID 41111955

Europe PMCDOI
2
hedged sentences
0.0510
closest p · 1.0× alpha
0.0510
boldest claim

The sentences

borderline significantp = 0.051so close (0.05 < p ≤ 0.1)
In this reduced model of five studies ( n = 2,464), the common-effect model yielded a borderline significant result (SMD = −0.079, 95% CI: −0.158 to 0.0004, p = 0.051), while the random-effects model remained non-significant (SMD = −0.077, 95% CI: −0.195 to 0.042, p = 0.204).

also in 11,409 other papers

borderline significanceno p-value reported
Sensitivity analyses indicated that several studies (Fu 2024, Hu 2023, Xu 2019, Xu 2024) attenuated the pooled effect, while exclusion of Li 2024 and Hu 2023 reduced heterogeneity to 40.7% but resulted in only borderline significance.

also in 7,017 other papers

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