Barely Significant
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Cardiovascular Health Effects and Synthetic Cooling Agents in E-Cigarettes Labeled as "Clear" Marketed in Massachusetts After the Tobacco Product Flavoring Ban.

J Am Heart Assoc · 2025 · PMC12533735 · PMID 40792641

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borderline significanceno p-value reported
In multivariable models among e‐cigarette users, the increase in systolic and diastolic BP and mean arterial pressure remained significantly higher in “clear” e‐cigarette users compared with non‐“clear” flavored e‐cigarette users with borderline significance for HR when adjusting for age, sex, frequency of combustible cigarette use, and number of puffs used in the acute use sessions (Table 3 ).

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