Barely Significant
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Orthopedic interventions and outcomes in patients with metastatic renal cell carcinoma: a systematic review.

Ther Adv Med Oncol · 2025 · PMC12536162 · PMID 41122311

1
hedged sentence
0.0520
closest p · 1.0× alpha
0.0520
boldest claim

The sentences

marginal significancep = 0.052so close (0.05 < p ≤ 0.1)
36 showed that patients treated with intensive local therapy (defined as en bloc resection, curettage, or RT with BED > 85 Gy) demonstrated significantly better OS ( p = 0.006) for those with solitary bone metastasis, but only marginal significance ( p = 0.052) for those with multiple bone metastases, when compared to those treated with less intensive (RT with BED < 85 Gy) or no therapy.

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