Liver-specific propanoate metabolism-derived 2-ethylhexanol as a novel biomarker for precise diagnosis and prognosis of hepatocellular carcinoma.

Biomark Res · 2025 · PMC12539108 · PMID 41121421

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Notably, two liver-specific genes, ALDH2 and ALDH1B1 , emerged as highly significant prognostic indicators, presenting hazard ratios of 1.87 (95% confidence interval [CI]: 1.18–2.90) and 1.64 (95% CI: 1.06–2.50), respectively (Fig. 1 E).

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