Effects of dietary supplementation with periplaneta americana-derived antimicrobial peptides on (PA-AMPs) growth performance, immune function, and gut health in yellow-feathered broilers.

Prevotellaceae_UCG-001 abundance alterations demonstrated significant associations with host immune responses and intestinal barrier function, exhibiting positive correlations with serum immunoglobulins (IgA, IgM; P < 0.05) and tight junction proteins (jejunal/ileal Claudin1/ZO-1, jejunal Occludin; P < 0.05), while showing negative correlations with systemic pro-inflammatory cytokines (IL-1β, IL-6; P < 0.05), ileal IL-1β/IL-6 ( P < 0.05), and highly significant inverse correlations ( P < 0.01) with oxidative stress markers (TNF-α, MDA) and compartment-specific inflammation (duodenal IL-6/TNF-α, jejunal IL-6).

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