Genome-scale metabolic modeling and machine learning unravel metabolic reprogramming and mast cell role in lung cancer: a multi-level analysis.

Transl Lung Cancer Res · 2025 · PMC12541863 · PMID 41132995

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highly significantno p-value reported

The analysis demonstrated a highly significant reduction in resting mast cell infiltration in cancerous lung tissues compared to healthy lung tissue (mean fraction ≈0.15 in healthy vs. ≈0.08 in cancer).

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