In the absence of selective isotope labeling, such topological matters are inconsequential to a chemist, but they may be significant to an NMR spectroscopist in the rare cases where the reactants have nonsymmetric nuclear spin states.
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In the absence of selective isotope labeling, such topological matters are inconsequential to a chemist, but they may be significant to an NMR spectroscopist in the rare cases where the reactants have nonsymmetric nuclear spin states.