Sex difference in the burden of rheumatic heart disease: Insights from the Global Burden of Disease Study 2021.

PLoS One · 2025 · PMC12543145 · PMID 41124189

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an increasing trendno p-value reported

However, sex differences in RHD were positively correlated with SDI, indicating an increasing trend with higher SDI.

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a decreasing trendno p-value reported

If the 95% CI of the corresponding EAPC estimate is > 0, the age – standardized indicator exhibits an upward trend; if < 0, it shows a decreasing trend; If the 95% confidence intervals contain 0, it means there is no statistically significant difference in trend alterations [ 11 ].

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