OR27-06 Testicular Function After Immune Checkpoint Inhibitors Treatment

J Endocr Soc · 2025 · PMC12545270

Europe PMC

hedged sentence

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closest p · 1.1× alpha

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boldest claim

The sentences

marginally significantp=0.053so close (0.05 < p ≤ 0.1)

Over a median follow-up of 2.8 years (IQR 1.7, 4.5 years), there was a marginally significant reduction in sperm output (34% reduction from baseline median of 193 to 127 million; p=0.053) and sperm density (30% reduction from 61 to 43 million/mL; p=0.075), with no significant changes in sperm motility or morphology, or serum LH, FSH and testosterone.

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