Barely Significant
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White matter lesion effect modification of aspirin and unfractionated heparin during endovascular stroke treatment.

Insights Imaging · 2025 · PMC12546164 · PMID 41123765

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an increasing trendno p-value reported
The control arm (patients allocated to receive neither aspirin nor heparin) showed an increasing trend in sICH rates across tertiles (2%, 2%, and 11%, respectively), suggesting a potential WML-sICH association independent of aspirin and heparin, though the low incidence precludes definitive conclusions.

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