Barely Significant
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Head and Neck Cancer Incidence, Mortality, and Disability-Adjusted Life Years From 1990 to 2021-A Systematic Analysis for the Global Burden of Disease Study.

Int Dent J · 2025 · PMC12546873 · PMID 41067099

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an increasing trendno p-value reported
Exceptions included lip and oral cavity cancer in the low-middle SDI region [EAPC: 0.17 (0.12-0.22)], and other pharyngeal cancers in both the low-middle SDI [EAPC: 0.58 (0.54-0.63)] and low SDI [EAPC: 0.34 (0.26-0.42)] regions, where DALYs showed an increasing trend.

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a decreasing trendno p-value reported
In contrast, laryngeal cancer (EAPC: -1.09 [-1.16 to -1.01]), and nasopharyngeal cancer (EAPC: -1.06 [-1.28 to -0.84]) showed a decreasing trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.