Stability and biocompatibility of hBD3 with different chiral configurations and their therapeutic efficacy in periodontitis.

iScience · 2025 · PMC12547225 · PMID 41142128

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a notable trendno p-value reported

Furthermore, the periodontal tissue demonstrated a notable trend toward repair accompanied by extremely low levels of inflammatory cell infiltration ( Figures 2 A–2C and 2F).

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a slight trendno p-value reported

Notably, at a treatment concentration of 100 μg/mL, r-hBD3 demonstrated a slight trend toward decreased cell viability; however, this difference was not statistically significant when compared to L-hBD3 and D-hBD3.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.