Evaluating the Enantioselective Neurotoxicity of Organophosphorus Pollutant Dioxabenzofos: Mechanistic Studies Employing Cellular, Molecular, and Computational Toxicology Assays.

However, the key conjugated effects are unstable in the neurotoxic response of AChE to ( R )-dioxabenzofos, which is consistent with the total change trend of the conjugated effects obtained from the dynamic experiment; namely, the conjugated effects presented a weakening trend in the toxic reaction of AChE with ( R )-dioxabenzofos, whereas the conjugated effects displayed an increasing trend in the neurotoxic reaction of AChE with ( S )-dioxabenzofos.

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