Barely Significant
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High-value utilization of brewers' spent grain in extruded corn-based foods: physicochemical, functional, and metabolomic insights.

Food Chem X · 2025 · PMC12547939 · PMID 41140583

2
hedged sentences
0.0100
closest p · 0.2× alpha
0.0100
boldest claim

The sentences

highly significantP < 0.01actually significant
Compared to the non-extruded group, the expression levels of these differential metabolites exhibit highly significant changes following extrusion treatment ( P < 0.01), suggesting that the extrusion process markedly activates the metabolic activity of this pathway.

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marginally significantno p-value reported
This analysis identified 48 pathways, among which the original p -value of the “Intestinal IgA network” pathway was 0.0011, and after FDR correction, it was 0.0916 (in the marginally significant range), but its Pathway Impact reached 1.0, suggesting that this pathway occupies a key topological position in the overall metabolic remodeling.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.