Single-cell transcriptomics of peripheral blood mononuclear cells indicates impaired immune and inflammatory responses in alcohol-associated hepatitis.

Average expression level was steadily increasing in the first half of pseudotime, then showed exponential increase of expression level in the later stage in lineage 1(CM-IM-NCM), while in lineage 2 (CM-IM) the average expression level was relatively steady across states, with an increasing trend at later IM stage. 4.

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