Effects of 8-Week High-Intensity Interval Training Intervention Regulating the SIRT1/PGC1α Pathway on Hippocampal Neuron Injury and Cognitive Impairment in Obese Rats.

Curr Dev Nutr · 2025 · PMC12549539 · PMID 41140914

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

marginally nonsignificantP = 0.053so close (0.05 < p ≤ 0.1)

For PGC1α protein, the interaction effect of obesity and exercise was marginally nonsignificant [ F (1,12) = 4.592; partial η 2 = 0.277; P = 0.053], whereas significant main effects were observed for obesity [ F (1,12) = 16.591; partial η 2 = 0.580; P = 0.002] and exercise [ F (1,12) = 9.762; partial η 2 = 0.449; P = 0.009].

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