Neoadjuvant chemotherapy impacts axillary lymph node positivity in early breast cancer (cT1-2N0M0) with negative axillary lymph nodes at diagnosis.

While NAC significantly reduced both PR SLN and PR TLN in patients aged 40–60 years, the differences were not statistically significant in the ≤40 or >60 age groups, despite a numerical trend toward higher rates with NAC ( Figures 2 , 3 ). cT-staging In accordance with the 7th edition of the AJCC guidelines, tumors were classified as cT1 (≤20 mm; n = 111) or cT2 (>20 mm-≤50 mm; n = 325) based on maximum tumor diameter before surgery.

also in 1,012 other papers