Early response prediction during radiotherapy in rectal cancer using sequential diffusion-weighted imaging at a magnetic resonance image-guided linear accelerator.

Phys Imaging Radiat Oncol · 2025 · PMC12550183 · PMID 41141225

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

close to significancep = 0.06so close (0.05 < p ≤ 0.1)

Investigating the ideal timepoint for discrimination of response by building the model with an increasing number of fractions resulted in no clear optimum but was close to significance at five (β 3 = 0.076 (CI [-0.001,0.153], p = 0.06)) and ten fractions (β 3 = 0.034 (CI [0.000,0.068], p = 0.05)), and then stabilised after around thirteen fractions ( Fig. 4A ).

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