Nicotine replacement therapy during the acute phase of aneurysmal subarachnoid hemorrhage.

Acta Neurochir (Wien) · 2025 · PMC12552259 · PMID 41134380

Europe PMC DOI

hedged sentence

0.0520

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

borderline significantp = 0.052so close (0.05 < p ≤ 0.1)

Higher age, WFNS, comorbidity, IVH, ICH, DCI-related infarction, and secondary respiratory failure were independent predictors of poor outcome, whereas NRT was not. In light smokers, NRT was a significant predictor of poor outcome in the univariate analysis (OR 2.926, 95% CI 1.220–7.020, p = 0.016) and borderline significant in the multivariate analysis (OR 3.245, 95% CI 0.911, 10.621, p = 0.052).

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