Effect of Acetazolamide on Pulmonary Hemodynamics and Right Heart Function in Healthy Adults Going to Altitude: A Randomized Controlled Trial.

Although there was an apparent trend toward lower sPAP in the acetazolamide group at high altitude, apart from not being statistically significant, these subtle changes (−2.1 ([95% CI, −4.4 to 0.3] mm Hg)) appear unlikely to be clinically relevant nor sufficient in preventing high‐altitude pulmonary edema.

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