MicroRNA-125b inhibits apoptosis and increases gemcitabine resistance by downregulating the expression of BAK1 in pancreatic ductal adenocarcinoma.

Transl Cancer Res · 2025 · PMC12554503 · PMID 41158265

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highly significantno p-value reported

Although BAK1 is not a core member of the Bcl-2 family or a commonly targeted molecule in drug development, exploring its potential as a therapeutic target for pancreatic cancer is highly significant ( 44 ).

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