The cortisol-treated WT zebrafish brain showed an almost significant increase in the distribution of M + 3 and M + 2 fumarate labeling with 1.3% and 2.2% in comparison to the WT control, which showed only 0.44% and 1.3%, respectively ( p = 0.052; Figure 8B ).
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Stable-isotope tracing reveals the role of corticosteroid receptors in driving cortisol-mediated central and peripheral glucose regulation in zebrafish.
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