Trends in Alzheimer's disease mortality in Espírito Santo, Brazil: a time series study.

Dement Neuropsychol · 2025 · PMC12561170 · PMID 41163776

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a positive trendno p-value reported

The estimated coefficient (β 1 ) was 48.16, and the APC was 5.48%, still reflecting a positive trend, though less pronounced than in the previous period.

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an increasing trendno p-value reported

The mean mortality rate due to AD was 15.31 deaths per 100 thousand inhabitants, with an increasing trend from 2013 to 2022, except for 2018, when a decrease was observed against 2017.

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highly significantno p-value reported

While the APC for all-cause mortality was 4.08%, the APC for AD mortality reached 8.84%, with an R 2 of 99.84% and a highly significant p-value (<0.001), suggesting a strong and linear growth pattern in AD-related deaths ( Table 4 ).

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