highly significantp = 9.39 × 10 −82
When comparing IBD genes to non-IBD genes within each tissue group, we observed highly significant differences across all categories: brain tissues ( p = 9.39 × 10 −82 ), GIT tissues ( p = 2.65 × 10 −97 ), and other tissues ( p = 1.17 × 10 −90 ), indicating that IBD-associated genes have distinct expression profiles compared to background genes.