Release of Mast Cell Mediators from Cochlear Tissue Following Short Exposure to Compound 48/80 or Cisplatin, and Their Damage to Cochlear Structure.

Cells · 2025 · PMC12562442 · PMID 41148830

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highly significantno p-value reported

Nonetheless, the consistent and highly significant damage observed at higher concentrations (1:400 and 1:20 dilutions) offers strong evidence for the ototoxic potential of MC mediators.

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