LDH-to-Albumin Ratio (LAR) in Solid Tumor Patients with Cytopenia: A Simple Biomarker to Predict Bone Marrow Metastasis.

HALP showed only borderline significance. According to the multivariate Cox regression model, male gender (HR: 2.024; 95% CI: 1.215–3.373; p = 0.007), elevated LAR (HR: 5.271; 95% CI: 2.611–10.641; p < 0.01), and the presence of concomitant bone metastasis (HR: 2.355; 95% CI: 1.262–4.393; p = 0.007) were identified as independent predictors for bone marrow metastasis ( Table 7 ).

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Although rare, it is highly significant in terms of disease progression [ 2 ].

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