Preclinical Application of Computer-Aided High-Frequency Ultrasound (HFUS) Imaging: A Preliminary Report on the In Vivo Characterization of Hepatic Steatosis Progression in Mouse Models.

J Imaging · 2025 · PMC12565216 · PMID 41150045

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This group showed no obvious changes in total entropy, energy, and correlation over time, while contrast showed a decreasing trend during the process of physiological aging (−40%), suggesting that GLCM contrast could be a useful parameter in detection of small, age- or disease-related changes in liver texture not visible with conventional HFUS.

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