Barely Significant
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Efficacy and Safety of Hyaluronic Acid Fillers for Midface Augmentation: A Systematic Review and Meta-Analysis.

Medicina (Kaunas) · 2025 · PMC12566132 · PMID 41155810

Europe PMCDOI
1
hedged sentence
0.7900
closest p · 15.8× alpha
0.7900
boldest claim

The sentences

highly significantp = 0.79not close (p > 0.1)
Global Aesthetic Improvement Scale (GAIS) Responder Rate The pooled analysis of three studies demonstrated a highly significant difference in responder rates between the hyaluronic acid (HA) and control groups (RR = 3.27, 95% CI: 2.26–4.75, p = 0.79; I 2 = 95%), while performing subgroup analysis the HA was comparable to other fillers (RR = 1.12, 95% CI: 0.84–1.50, p = 0.43), while the HA was significantly superior to placebo group (RR = 53.62, 95% CI: 7.15–402.01, p = 0.0001).

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