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Therapeutic effects of Poncirus fructus on colonic dysfunction and visceral pain in a zymosan-induced irritable bowel syndrome mouse model through interstitial cells of Cajal and ion channel modulation.

Front Pharmacol · 2025 · PMC12569543 · PMID 41170383

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a decreasing trendno p-value reported
Although an increase in Firmicutes is commonly reported in IBS ( Duan et al., 2019 ), our study observed a decreasing trend.

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