Barely Significant
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Global and regional burden of kidney cancer from 1990 to 2021: analysis and future predictions based on global burden of disease study.

BMC Cancer · 2025 · PMC12570411 · PMID 41152725

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an overall trendno p-value reported
A review of data from 1996 to 2004 indicated that kidney cancer had the highest mortality rate among all genitourinary cancers in the United States; however, there has been an overall trend toward a decrease in the mortality rate of kidney cancer since the mid-1990s [ 6 ].

also in 4,871 other papers

a decreasing trendno p-value reported
Forty-nine countries or regions, mainly in Western Europe and North America, had a decreasing trend in ASR for mortality over the period.

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.