Systematic review and meta-analysis of cardiovascular associated biomarkers in adults with asymptomatic autoimmune diseases.

Front Cardiovasc Med · 2025 · PMC12571752 · PMID 41179568

Europe PMC DOI

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closest p

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highly significantp = 0.00not a probability at all

Despite this variability, the overall effect was highly significant ( z = 15.43, p = 0.00).

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borderline significantno p-value reported

A REML model yielded a pooled HR of 1.59 (95% CI: 0.99–2.06), indicating a borderline significant association ( Figure 8A ).

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borderline significanceno p-value reported

In contrast, rheumatoid factor, anti-CCP, ADMA, homocysteine, NT-proBNP, anti-dsDNA, and TNF-alpha showed borderline significance or inconsistent results.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.