Increased Antidepressant Prescriptions for Children and Adolescents with Major Depressive Disorder in Japan Based on a Claims Database.

By drug class, a higher proportion of selective serotonin reuptake inhibitors, especially sertraline and escitalopram, were prescribed in any given FY, with an increasing trend in the 13–18 age group (2.64/1000 persons in 2010, 3.55/1000 persons in 2017).

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Since escitalopram’s launch in FY2011, its prescription has steadily increased in the 13–18 age group, whereas the rate of fluvoxamine prescriptions showed a decreasing trend.

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