CRISPR-mediated engineering of mesenchymal stromal/stem cells: a summary of recent progress in immunological applications for regenerative medicine and cancer therapy.

Stem Cell Res Ther · 2025 · PMC12574024 · PMID 41163074

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highly significantno p-value reported

The critical finding that PD-L1-deficient MSC-derived exosome retains this activating property is highly significant, as it opens promising avenues for safer, more manageable cell-free cancer immunotherapies.

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