There was also a significant reduction in exhausted TIM3 + CD8 + T cells and a notable trend in increased NK T cells (Fig. 3 B and C), suggesting that the modulation of TAM polarization also influenced other tumor-associated immune cells, including T cells.
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Locally Reprogramming Tumor-Associated Macrophages with Cytokine-Loaded Injectable Cryogels for Breast Cancer.
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