Multi-modal omics analysis of a paediatric melanoma highlights mechanisms underlying treatment resistance.

Commun Med (Lond) · 2025 · PMC12575648 · PMID 41168392

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a notable trendno p-value reported

Although the expression levels of MITF and BRAF across the analysed ROIs—spanning primary tumours, lymph node metastases, and cutaneous metastases—did not show significant differences, the analysis of a gene signature associated with ICI failure 29 revealed a notable trend.

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