Implications for optimizing treatment timing: day of week variation in PTSD symptom clusters.

Among participants with PTSD, the weekday and weekend differences were attenuated but remained significant or marginally significant when random slopes for weekday and weekend differences were included, (intrusion: p = .056, avoidance: p = .031, negative cognitions: p = .012, and hyperarousal: p <.001). 4 Discussion Using an EMA approach, this study examined the day of the week variation in each of the DSM-5 PTSD symptom clusters (intrusion, avoidance, negative cognitions/mood, and hyperarousal) across 15 days in individuals with and without PTSD.

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