Barely Significant
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Depression Polygenicity and Disease Activity and Disability Worsening in Multiple Sclerosis.

Ann Neurol · 2025 · PMC12577672 · PMID 40772555

Europe PMCDOI
1
hedged sentence
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

marginally significantp = 0.050actually significant
In the Kaplan–Meier analysis, PwMS in the highest depression PGS (top 20%) experienced more protocol‐defined relapses compared to the bottom 80% depression PGS quantile, albeit this was marginally significant (Table 2 ) ( p = 0.050).

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