Over the past 30 years, the proportion of RCTs related to pharmacological therapy showed an increasing trend from 0 of 8 trials between 1995 and 1999 to 18 of 74 trials (24.3%) between 2010 and 2014 and then decreased to only 5 of 75 trials (6.7%) between 2020 and 2024.
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Research waste in randomized clinical trials of degenerative spinal diseases: a cross-sectional study.
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