The IgG Paradox in Lipedema: More Food Sensitivities, Less Antibody Production.

Cureus · 2025 · PMC12579957 · PMID 41185844

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

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highly significantp<0.001actually significant

This finding, combined with the highly significant differences in total IgG levels (p<0.001), suggests a complex immunological pattern in lipedema characterized by altered antibody production rather than simply increased food reactivity.

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